Modeling the resonance Raman spectrum of a metarhodopsin: implications for the color of visual pigments

M. Sulkes, A. Lewis, A. T. Lemley, R. Cookingham

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Resonance Raman spectra of an invertebrate rhodopsin are reported. The spectrum of squid acid metarhodopsin is compared with the spectra of model compounds of the retinylidene chromophore in the all trans conformation. Correlations made between acid metarhodopsin and these crystalline model compounds with known x ray structures indicate that the chromophore in this intermediate is an all trans protonated Schiff base. The data suggest a mechanism for the red shift in rhodopsin.

Original languageEnglish
Pages (from-to)4266-4270
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume73
Issue number12
DOIs
StatePublished - 1976
Externally publishedYes

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