Modeling WWOX loss of function in vivo: What have we learned?

Keyphrases

• Rodents 100%
• Loss Function 100%
• Homeostasis 50%
• Growth Retardation 50%
• WW Domain 50%
• In Cancer 50%
• WW Domain-containing Oxidoreductase 50%
• Common Fragile Sites 50%
• FRA16D 50%
• WWOX Gene 50%
• Deregulation 50%
• Physiological Homeostasis 50%
• C-terminus 50%
• Neuropathy 50%
• Sequence Conservation 50%
• Tumorigenesis 50%
• Adaptor Protein 50%
• Orthologues 50%
• Catalytic Domain 50%
• Metabolic Disorders 50%
• Essential Proteins 50%
• Perinatal Lethality 50%
• Short-chain Dehydrogenase/reductase 50%
• Family Proteins 50%

Biochemistry, Genetics and Molecular Biology

• WWOX 100%
• Homeostasis 28%
• Oxidoreductase 28%
• WW Domain 28%
• C-Terminus 14%
• N-Terminus 14%
• Short-Chain Dehydrogenase 14%
• Reductase 14%
• Animal Model 14%
• Protein Family 14%
• Carcinogenesis 14%
• Enzyme Active Site 14%
• Metabolic Disorder 14%