Modulating calmodulin binding specificity through computational protein design

Keyphrases

• Binding Specificity 100%
• Computational Protein Design 100%
• Calmodulin 100%
• Smooth muscle Myosin 40%
• Myosin Light Chain Kinase 40%
• Targeting Peptide 20%
• Amino Acid Residues 10%
• Binding Interface 10%
• Binding Affinity 10%
• Low Energy 10%
• Protein Design 10%
• Protein-protein Interface 10%
• Ca2+-binding Protein 10%
• Force Field 10%
• Protein Receptor 10%
• Novel Protein 10%
• Protein Scaffold 10%
• Iterative Methods 10%
• Design Project 10%
• Computational Redesign 10%
• Rotamers 10%
• Physically-based 10%
• Protein-ligand Complex 10%
• Dead-time Elimination 10%
• Natural Targets 10%

Biochemistry, Genetics and Molecular Biology

• Protein Design 100%
• Calmodulin Binding 100%
• Calmodulin 100%
• Myosin Light-Chain Kinase 50%
• Binding Protein 25%
• Target Peptide 25%
• Amino Acids 12%
• Wild Type 12%
• Binding Affinity 12%
• Scaffold Protein 12%
• Protein Ligand 12%