Modulation of MKNK2 alternative splicing by splice-switching oligonucleotides as a novel approach for glioblastoma treatment

Keyphrases

• Alternative Splicing 100%
• Splice-switching Oligonucleotides 100%
• MKNK2 100%
• Glioblastoma Therapy 100%
• Glioblastoma 50%
• P38 Mitogen-activated Protein Kinase (p38 MAPK) 50%
• Pro-oncogenic 50%
• Glioblastoma Cells 50%
• Apoptosis 25%
• Cancer Types 25%
• Tumor Suppressor 25%
• Overexpression 25%
• Tumor Suppression 25%
• Chemotherapy 25%
• Induced Transformations 25%
• Tumorigenesis 25%
• Stress Response Pathway 25%
• Antisense Oligonucleotides 25%
• Oncogenic Activity 25%
• Anti-oncogenic 25%
• Oncogenic Properties 25%
• P38 MAPK Pathway 25%
• Oncogenic Factor 25%
• Modified RNA 25%

Biochemistry, Genetics and Molecular Biology

• Oligonucleotide 100%
• Isoform 100%
• Alternative Splicing 100%
• Tumor Suppressor Protein 33%
• Phosphotransferase 33%
• Kinase 33%
• Carcinogenesis 33%
• Antisense RNA 33%

Neuroscience

• Alternative Splicing 100%
• Oligonucleotide 100%
• In Vivo 66%
• Kinase 33%
• Carcinogenesis 33%
• Antisense RNA 33%
• Antisense Oligonucleotide 33%
• Tumor Suppressor Protein 33%