Modulation of the 3′,5′-cyclic AMP content by the respiration rate in E. coli K-12

Rachel Hertz*, Jacob Bar-Tana

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Flagellation and β-galactosidase activity were repressed in electron transport-deficient mutants of Escherichia coli K-12. The repressed state was alleviated upon restoring respiration capacity or in the presence of added 3′,5′-cyclic AMP. The repressed/derepressed states observed with varying respiration rates were due to modulation of the intracellular 3′,5′-cyclic AMP content effected by respective changes in the activity of adenylate cyclase as a function of respiration rate.

Original languageEnglish
Pages (from-to)193-199
Number of pages7
JournalArchives of Biochemistry and Biophysics
Volume213
Issue number1
DOIs
StatePublished - Jan 1982

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