Keyphrases
Network Analysis
100%
Molecular Dynamics Simulation
100%
Elastic Network
100%
Akt PKB
100%
Protein Kinase B/Akt
100%
Simulation Network
100%
First Principals
66%
Normal Mode Analysis
66%
Activation Loop
66%
Elastic Network Model
66%
Molecular Dynamics Trajectories
66%
Trajectory Analysis
33%
Conformational Change
33%
Strong Correlation
33%
Computational Study
33%
Cell Proliferation
33%
Cell Survival
33%
Dynamic Process
33%
Specific Inhibitor
33%
Inhibitor Design
33%
Protonation State
33%
Catalytic Domain
33%
Dephosphorylation
33%
Analysis Mode
33%
Crystalline Structure
33%
Anticorrelation
33%
Anti-oncogenic
33%
Phosphoinositide 3-kinase Signaling Pathway
33%
N-lobe
33%
C-helix
33%
Apo Structure
33%
Protein Kinase B
33%
Complex Trajectories
33%
Phosphorylated Akt
33%
Phosphothreonine
33%
Number of Principal Components
33%
C-lobe
33%
Activated State
33%
Biochemistry, Genetics and Molecular Biology
Phosphotransferase
100%
Kinase
100%
Protein Characterization
100%
Protein Kinase B
100%
Computer Simulation
100%
Motion
75%
Dynamics
75%
Conformational Change
25%
Signal Transduction
25%
Cell Survival
25%
Cell Proliferation
25%
Protonation
25%
Phosphoinositide 3-Kinase
25%
Dephosphorylation
25%
Enzyme Active Site
25%
Crystal Structure
25%