TY - JOUR
T1 - Molecular mechanisms and genomic maps of DNA excision repair in Escherichia coli and humans
AU - Hu, Jinchuan
AU - Selby, Christopher P.
AU - Adar, Sheera
AU - Adebali, Ogun
AU - Sancar, Aziz
N1 - Publisher Copyright:
© 2017 by The American Society for Biochemistry and Molecular Biology, Inc.
PY - 2017/9/22
Y1 - 2017/9/22
N2 - Nucleotide excision repair is a major DNA repair mechanism in all cellular organisms. In this repair system, the DNA damage is removed by concerted dual incisions bracketing the damage and at a precise distance from the damage. Here, we review the basic mechanisms of excision repair in Escherichia coli and humans and the recent genome-wide mapping of DNA damage and repair in these organisms at single-nucleotide resolution.
AB - Nucleotide excision repair is a major DNA repair mechanism in all cellular organisms. In this repair system, the DNA damage is removed by concerted dual incisions bracketing the damage and at a precise distance from the damage. Here, we review the basic mechanisms of excision repair in Escherichia coli and humans and the recent genome-wide mapping of DNA damage and repair in these organisms at single-nucleotide resolution.
UR - http://www.scopus.com/inward/record.url?scp=85029759628&partnerID=8YFLogxK
U2 - 10.1074/jbc.R117.807453
DO - 10.1074/jbc.R117.807453
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C2 - 28798238
AN - SCOPUS:85029759628
SN - 0021-9258
VL - 292
SP - 15588
EP - 15597
JO - Journal of Biological Chemistry
JF - Journal of Biological Chemistry
IS - 38
ER -