Abstract
Nucleotide excision repair is a major DNA repair mechanism in all cellular organisms. In this repair system, the DNA damage is removed by concerted dual incisions bracketing the damage and at a precise distance from the damage. Here, we review the basic mechanisms of excision repair in Escherichia coli and humans and the recent genome-wide mapping of DNA damage and repair in these organisms at single-nucleotide resolution.
| Original language | English |
|---|---|
| Pages (from-to) | 15588-15597 |
| Number of pages | 10 |
| Journal | Journal of Biological Chemistry |
| Volume | 292 |
| Issue number | 38 |
| DOIs | |
| State | Published - 22 Sep 2017 |
Bibliographical note
Publisher Copyright:© 2017 by The American Society for Biochemistry and Molecular Biology, Inc.
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