Monocyte chemoattractant protein-1 blockade inhibits lung cancer tumor growth by altering macrophage phenotype and activating CD8⁺ cells

Keyphrases

• Antitumor 8%
• Antitumor Effect 8%
• Cancer Tumor 100%
• CD8+ Cells 100%
• CD8+ Cytotoxic T Lymphocytes 8%
• CD8+ T Cells 8%
• CD8+ T Lymphocytes 8%
• Chemokine (C-C motif) Ligand 2 (CCL2) 100%
• Chemokines 8%
• Lung Cancer 100%
• Lung Cancer Model 8%
• Lung Metastasis 16%
• Macrophage Phenotype 100%
• Metastatic Disease 8%
• Monoclonal Antibody 8%
• Monocyte Chemoattractant protein-1 (MCP-1) 100%
• Neutralizing Antibodies 8%
• Non-small Cell Lung Cancer (NSCLC) 33%
• Orthotopic Model 8%
• Primary Disease 8%
• Primary Tumor 8%
• Pro-tumorigenic 8%
• Severe Combined Immunodeficient Mice 8%
• Solid Tumors 8%
• Syngeneic 8%
• T Cell Depletion 8%
• Thoracic Malignancy 8%
• Treatment Effect 8%
• Tumor 8%
• Tumor Cells 8%
• Tumor Growth 100%
• Tumor Stromal Cells 8%
• Tumor-associated 8%
• Tumor-associated Macrophages 25%
• Tumorigenesis 8%
• Work Support 8%

Immunology and Microbiology

• CCL2 100%
• CD8+ Cell 100%
• CD8+ T Lymphocyte 16%
• Chemokine 8%
• Cytotoxic T-Cell 8%
• Flank 8%
• Macrophage 100%
• Monoclonal Antibody 8%
• Monocyte Chemotactic Protein 1 100%
• Murine 8%
• Neutralizing Antibody 8%
• SCID Mouse 8%
• Syngenic 8%
• T Cell Depletion 8%
• Tumor Cell 8%
• Tumor-Associated Macrophage 16%