Monosaccharide-Derived Enantioselectivity in SWCNT Chemoresistive VOC Sensing

Semiconducting single-walled carbon nanotubes (sc-SWCNTs) are of great potential for vapor sensing. However, sc-SWCNTs lack recognition features for discriminating between sparsely functionalized moieties, molecules with similar structural features, and enantiomer pairs. This becomes a major setback in discriminating between volatile organic compounds (VOCs). Here, we used two galactosides decorated with aromatic groups as a recognition layer in chemoresistive sc-SWCNT sensors to produce chiral preference toward six terpenoid enantiomers. The multichirality and multifunctionality of a monosaccharide scaffold were exploited to maximize the limited interacting features associated with VOCs. The developed system establishes a robust and tunable platform for enantioselective gas sensing.