Moving towards totipotency without a single miR-acle

Noam Maoz, Yosef Buganim*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Totipotency is the ability of a single cell to form an entire embryo, including extraembryonic tissues, an ability we have yet to recapitalize, in vitro. In a recent paper published in Science, Choi et al. showed that pluripotent stem cells lacking microRNA miR-34a, have an expanded cell fate potential allowing differentiation into not only embryonic but also extraembryonic lineages.

Original languageAmerican English
Pages (from-to)600-601
Number of pages2
JournalCell Research
Issue number5
StatePublished - 1 May 2017

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© 2017 IBCB, SIBS, CAS All rights reserved.


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