Moving towards totipotency without a single miR-acle

Noam Maoz; Yosef Buganim

doi:10.1038/cr.2017.30

Moving towards totipotency without a single miR-acle

Noam Maoz, Yosef Buganim^*

^*Corresponding author for this work

Department of Developmental Biology and Cancer Research

Research output: Contribution to journal › Review article › peer-review

Abstract

Totipotency is the ability of a single cell to form an entire embryo, including extraembryonic tissues, an ability we have yet to recapitalize, in vitro. In a recent paper published in Science, Choi et al. showed that pluripotent stem cells lacking microRNA miR-34a, have an expanded cell fate potential allowing differentiation into not only embryonic but also extraembryonic lineages.

Original language	English
Pages (from-to)	600-601
Number of pages	2
Journal	Cell Research
Volume	27
Issue number	5
DOIs	https://doi.org/10.1038/cr.2017.30
State	Published - 1 May 2017

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10.1038/cr.2017.30

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Moving towards totipotency without a single miR-acle

Abstract

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