Multi-Dimensional Laboratory Test Score as a Proxy for Health

Bar H. Ezra; Shreyas Havaldar; Benjamin Glicksberg; Nadav Rappoport

doi:10.3233/SHTI220441

Multi-Dimensional Laboratory Test Score as a Proxy for Health

Bar H. Ezra
, Shreyas Havaldar
, Benjamin Glicksberg
, Nadav Rappoport^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

The standard of care for a physician to review laboratory tests results is to weigh each individual laboratory test result and compare it to against a standard reference range. Such a method of scanning can lead to missing high-level information. Different methods have tried to overcome a part of the problem by creating new types of reference values. This research proposes looking at test scores in a higher dimension space. And using machine learning approach, determine whether a subject has abnormal tests result that, according to current practice, would be defined as valid-and thus indicating a possible disease or illness. To determine health status, we look both at a disease-specific level and disease-independent level, while looking at several different outcomes.

Original language	English
Title of host publication	Challenges of Trustable AI and Added-Value on Health - Proceedings of MIE 2022
Editors	Brigitte Seroussi, Patrick Weber, Ferdinand Dhombres, Cyril Grouin, Jan-David Liebe, Jan-David Liebe, Jan-David Liebe, Sylvia Pelayo, Andrea Pinna, Bastien Rance, Bastien Rance, Lucia Sacchi, Adrien Ugon, Adrien Ugon, Arriel Benis, Parisis Gallos
Publisher	IOS Press BV
Pages	219-223
Number of pages	5
ISBN (Electronic)	9781643682846
DOIs	https://doi.org/10.3233/SHTI220441
State	Published - 25 May 2022
Externally published	Yes
Event	32nd Medical Informatics Europe Conference, MIE 2022 - Nice, France Duration: 27 May 2022 → 30 May 2022

Publication series

Name	Studies in Health Technology and Informatics
Volume	294
ISSN (Print)	0926-9630
ISSN (Electronic)	1879-8365

Conference

Conference	32nd Medical Informatics Europe Conference, MIE 2022
Country/Territory	France
City	Nice
Period	27/05/22 → 30/05/22

Bibliographical note

Publisher Copyright:
© 2022 European Federation for Medical Informatics (EFMI) and IOS Press.

Keywords

Electronic Health Records
Laboratory Tests
Machine Learning
UK Biobank

Access to Document

10.3233/SHTI220441

Cite this

Ezra, B. H., Havaldar, S., Glicksberg, B., & Rappoport, N. (2022). Multi-Dimensional Laboratory Test Score as a Proxy for Health. In B. Seroussi, P. Weber, F. Dhombres, C. Grouin, J.-D. Liebe, J.-D. Liebe, J.-D. Liebe, S. Pelayo, A. Pinna, B. Rance, B. Rance, L. Sacchi, A. Ugon, A. Ugon, A. Benis, & P. Gallos (Eds.), Challenges of Trustable AI and Added-Value on Health - Proceedings of MIE 2022 (pp. 219-223). (Studies in Health Technology and Informatics; Vol. 294). IOS Press BV. https://doi.org/10.3233/SHTI220441

Ezra, Bar H. ; Havaldar, Shreyas ; Glicksberg, Benjamin et al. / Multi-Dimensional Laboratory Test Score as a Proxy for Health. Challenges of Trustable AI and Added-Value on Health - Proceedings of MIE 2022. editor / Brigitte Seroussi ; Patrick Weber ; Ferdinand Dhombres ; Cyril Grouin ; Jan-David Liebe ; Jan-David Liebe ; Jan-David Liebe ; Sylvia Pelayo ; Andrea Pinna ; Bastien Rance ; Bastien Rance ; Lucia Sacchi ; Adrien Ugon ; Adrien Ugon ; Arriel Benis ; Parisis Gallos. IOS Press BV, 2022. pp. 219-223 (Studies in Health Technology and Informatics).

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abstract = "The standard of care for a physician to review laboratory tests results is to weigh each individual laboratory test result and compare it to against a standard reference range. Such a method of scanning can lead to missing high-level information. Different methods have tried to overcome a part of the problem by creating new types of reference values. This research proposes looking at test scores in a higher dimension space. And using machine learning approach, determine whether a subject has abnormal tests result that, according to current practice, would be defined as valid-and thus indicating a possible disease or illness. To determine health status, we look both at a disease-specific level and disease-independent level, while looking at several different outcomes.",

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note = "Publisher Copyright: {\textcopyright} 2022 European Federation for Medical Informatics (EFMI) and IOS Press.; 32nd Medical Informatics Europe Conference, MIE 2022 ; Conference date: 27-05-2022 Through 30-05-2022",

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Ezra, BH, Havaldar, S, Glicksberg, B & Rappoport, N 2022, Multi-Dimensional Laboratory Test Score as a Proxy for Health. in B Seroussi, P Weber, F Dhombres, C Grouin, J-D Liebe, J-D Liebe, J-D Liebe, S Pelayo, A Pinna, B Rance, B Rance, L Sacchi, A Ugon, A Ugon, A Benis & P Gallos (eds), Challenges of Trustable AI and Added-Value on Health - Proceedings of MIE 2022. Studies in Health Technology and Informatics, vol. 294, IOS Press BV, pp. 219-223, 32nd Medical Informatics Europe Conference, MIE 2022, Nice, France, 27/05/22. https://doi.org/10.3233/SHTI220441

Multi-Dimensional Laboratory Test Score as a Proxy for Health. / Ezra, Bar H.; Havaldar, Shreyas; Glicksberg, Benjamin et al.
Challenges of Trustable AI and Added-Value on Health - Proceedings of MIE 2022. ed. / Brigitte Seroussi; Patrick Weber; Ferdinand Dhombres; Cyril Grouin; Jan-David Liebe; Jan-David Liebe; Jan-David Liebe; Sylvia Pelayo; Andrea Pinna; Bastien Rance; Bastien Rance; Lucia Sacchi; Adrien Ugon; Adrien Ugon; Arriel Benis; Parisis Gallos. IOS Press BV, 2022. p. 219-223 (Studies in Health Technology and Informatics; Vol. 294).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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A2 - Pelayo, Sylvia

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A2 - Rance, Bastien

A2 - Sacchi, Lucia

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Ezra BH, Havaldar S, Glicksberg B, Rappoport N. Multi-Dimensional Laboratory Test Score as a Proxy for Health. In Seroussi B, Weber P, Dhombres F, Grouin C, Liebe JD, Liebe JD, Liebe JD, Pelayo S, Pinna A, Rance B, Rance B, Sacchi L, Ugon A, Ugon A, Benis A, Gallos P, editors, Challenges of Trustable AI and Added-Value on Health - Proceedings of MIE 2022. IOS Press BV. 2022. p. 219-223. (Studies in Health Technology and Informatics). doi: 10.3233/SHTI220441

Multi-Dimensional Laboratory Test Score as a Proxy for Health

Abstract

Publication series

Conference

Bibliographical note

Keywords

Access to Document

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