Multimodal monitoring of human brain organoids implanted in mice using transparent microelectrodes

Martin Thunemann*, Madison Wilson, Francesca Puppo, Donald P. Pizzo, Hannah Rickner, Emma Bortz, Abed Al Fatah Mansour, Benjamin Wolozin, Xue Han, Fred H. Gage, Alysson R. Muotri, Duygu Kuzum, Anna Devor

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

Abstract

We present an in vivo platform merging stem cell technology, two-photon imaging, and electrophysiology with transparent graphene microelectrodes for longitudinal interrogation of human brain organoids implanted in the cortex of immunodeficient mice.

Original languageAmerican English
Article numberBM2B.4
JournalOptics InfoBase Conference Papers
StatePublished - 2021
Externally publishedYes
EventOptics and the Brain, BRAIN 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021 - Virtual, Online, United States
Duration: 12 Apr 202116 Apr 2021

Bibliographical note

Publisher Copyright:
© 2021 The Author(s).

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