TY - JOUR
T1 - Multiple eaulsions. part II
T2 - Proposed technique to overcome unpleasant taste of drugs
AU - Garti, Nissim
AU - Frenkel, Moshe
AU - Shwartz, Rosi
PY - 1983/1/1
Y1 - 1983/1/1
N2 - Multiple emulsions of water in oil in water (W/O/W) have been used as a novel technique to overcome unpleasant taste of drugs. The drug is dissolved in the inner water phase and is released throughout the oil phase in the presence of synthetic gastric juice. Yield of preparation and stability have been studied using various sets of different inner (emulsifier I) and outer (emulsifier II) emulsifiers. Combination of anionic-nonionic emulsifiers yielded optimal results: High yield of preparation, high stability and complete release of the drug in synthetic gastric juice.
AB - Multiple emulsions of water in oil in water (W/O/W) have been used as a novel technique to overcome unpleasant taste of drugs. The drug is dissolved in the inner water phase and is released throughout the oil phase in the presence of synthetic gastric juice. Yield of preparation and stability have been studied using various sets of different inner (emulsifier I) and outer (emulsifier II) emulsifiers. Combination of anionic-nonionic emulsifiers yielded optimal results: High yield of preparation, high stability and complete release of the drug in synthetic gastric juice.
UR - http://www.scopus.com/inward/record.url?scp=0020889335&partnerID=8YFLogxK
U2 - 10.1080/01932698308943369
DO - 10.1080/01932698308943369
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AN - SCOPUS:0020889335
SN - 0193-2691
VL - 4
SP - 237
EP - 252
JO - Journal of Dispersion Science and Technology
JF - Journal of Dispersion Science and Technology
IS - 3
ER -