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Multistep, effective drug distribution within solid tumors
Amotz Shemi
*
, Elina Zorde Khvalevsky
, Rachel Malka Gabai
,
Abraham Domb
,
Yechezkel Barenholz
*
Corresponding author for this work
School of Pharmacy
Alexander Silberman Institute of Life Sciences
Research output
:
Contribution to journal
›
Article
›
peer-review
27
Scopus citations
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Keyphrases
Tumor
100%
Effective Compounds
100%
Solid Tumors
100%
Drug Distribution
100%
Convection
50%
Pancreatic Cancer
50%
Pressure Gradient
50%
Interstitial Fluid Pressure
50%
Steady State
25%
Multi-step Process
25%
Perfusion
25%
Lymphatics
25%
Cancer Patients
25%
Cancer Therapy
25%
Drug Penetration
25%
Cell Layer
25%
Intratumoral Injection
25%
Small Interfering RNA (siRNA)
25%
In Vivo Model
25%
Blood Flow
25%
Body Movement
25%
Hydraulics
25%
Tumor Cell Death
25%
Systemic Delivery
25%
Void Volume
25%
Mutated KRAS
25%
Lymph Flow
25%
Tumor Core
25%
Phase 1/2 Clinical Trial
25%
Antitumor Drug Delivery
25%
Drug Sources
25%
Pharmacology, Toxicology and Pharmaceutical Science
Neoplasm
100%
Solid Malignant Neoplasm
100%
Drug Distribution
100%
Pancreas Cancer
40%
Malignant Neoplasm
20%
Clinical Trial
20%
Small Interfering RNA
20%