Mutation rate and pattern of microsatellites in common carp (Cyprinus carpio L.)

G. H. Yue; L. David; L. Orban

doi:10.1007/s10709-006-0003-8

Mutation rate and pattern of microsatellites in common carp (Cyprinus carpio L.)

G. H. Yue^*, L. David, L. Orban

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

64 Scopus citations

Abstract

Microsatellites are popular molecular markers in genetic and evolutionary studies. Their mutational dynamics have been extensively studied in humans and fruit flies, but few data were available in fish. By genotyping 55 individuals of a F1 pedigree, we investigated the mutation rates and patterns of 49 microsatellites in one of the most important fresh water fish species, the common carp (Cyprinus carpio L.). The overall mutation rate of the 49 loci was 5.56×10^-4/locus/generation (95% confidence interval 1.52×10^-4 and 1.63×10^-3). The change of allele size was between +2 to -5 repeat units, assuming that the mutation allele arose from the parental allele most similar in size to the mutant.

Original language	English
Pages (from-to)	329-331
Number of pages	3
Journal	Genetica
Volume	129
Issue number	3
DOIs	https://doi.org/10.1007/s10709-006-0003-8
State	Published - Mar 2007
Externally published	Yes

Bibliographical note

Funding Information:
Acknowledgments This study was supported by the internal research fund from the Temasek Life Sciences Laboratory, Singapore.

Keywords

Cyprinids
Evolution
Mutation dynamics
Population genetics
Stepwise Mutation Model

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10.1007/s10709-006-0003-8

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abstract = "Microsatellites are popular molecular markers in genetic and evolutionary studies. Their mutational dynamics have been extensively studied in humans and fruit flies, but few data were available in fish. By genotyping 55 individuals of a F1 pedigree, we investigated the mutation rates and patterns of 49 microsatellites in one of the most important fresh water fish species, the common carp (Cyprinus carpio L.). The overall mutation rate of the 49 loci was 5.56×10-4/locus/generation (95% confidence interval 1.52×10-4 and 1.63×10-3). The change of allele size was between +2 to -5 repeat units, assuming that the mutation allele arose from the parental allele most similar in size to the mutant.",

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doi = "10.1007/s10709-006-0003-8",

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AU - David, L.

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Mutation rate and pattern of microsatellites in common carp (Cyprinus carpio L.)

Abstract

Bibliographical note

Keywords

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