Mutation rate and pattern of microsatellites in common carp (Cyprinus carpio L.)

G. H. Yue*, L. David, L. Orban

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

63 Scopus citations

Abstract

Microsatellites are popular molecular markers in genetic and evolutionary studies. Their mutational dynamics have been extensively studied in humans and fruit flies, but few data were available in fish. By genotyping 55 individuals of a F1 pedigree, we investigated the mutation rates and patterns of 49 microsatellites in one of the most important fresh water fish species, the common carp (Cyprinus carpio L.). The overall mutation rate of the 49 loci was 5.56×10-4/locus/generation (95% confidence interval 1.52×10-4 and 1.63×10-3). The change of allele size was between +2 to -5 repeat units, assuming that the mutation allele arose from the parental allele most similar in size to the mutant.

Original languageAmerican English
Pages (from-to)329-331
Number of pages3
JournalGenetica
Volume129
Issue number3
DOIs
StatePublished - Mar 2007
Externally publishedYes

Bibliographical note

Funding Information:
Acknowledgments This study was supported by the internal research fund from the Temasek Life Sciences Laboratory, Singapore.

Keywords

  • Cyprinids
  • Evolution
  • Mutation dynamics
  • Population genetics
  • Stepwise Mutation Model

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