Near-field optics: From subwavelength illumination to nanometric shadowing

Aaron Lewis, Hesham Taha, Alina Strinkovski, Alexandra Manevitch, Artium Khatchatouriants, Rima Dekhter, Erich Ammann

Research output: Contribution to journalReview articlepeer-review

174 Scopus citations

Abstract

Near-field optics uniquely addresses problems of x, y and z resolution by spatially confining the effect of a light source to nanometric domains. The problems in using far-field optics (conventional optical imaging through a lens) to achieve nanometric spatial resolution are formidable. Near-field optics serves a bridging role in biology between optical imaging and scanned probe microscopy. The integration of near-field and scanned probe imaging with far-field optics thus holds promise for solving the so-called inverse problem of optical imaging.

Original languageEnglish
Pages (from-to)1378-1386
Number of pages9
JournalNature Biotechnology
Volume21
Issue number11
DOIs
StatePublished - Nov 2003

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