Necrotizing choroiditis-retinitis as presenting symptom of disseminated aspergillosis after lung transplantation

I. Anteby, M. Kramer, G. Rahav, D. Benezra

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Background. Endogenous endophthalmitis due to Aspergillus is rare affecting the severely immunosuppressed population, in particular recipients of heart and lung transplants. Ocular involvement of aspergillosis has always been observed late in the course of the disease. Subject. A young woman noted blurred vision in one eye three weeks after lung transplantation. At this stage, no systemic, manifestations of fungal infection were detected and the ocular findings were attributed to viral infection. Results. Twenty-four hours after the original ocular complaint, an aggressive endophthalmitis developed in the left eye. The possibility of fungal endophthalmitis was raised. Within 48 hours of her first ocular complaint the patient died. Cultures from a vitreous tap and from autopsy ocular specimens were positive for Aspergillus fumigatus. Conclusions. Aspergillus endophthalmitis may occur in patients undergoing lung transplantation despite antifungal therapy. Increased awareness of this unusual entity maybe life and vision saving in these patients.

Original languageAmerican English
Pages (from-to)294-296
Number of pages3
JournalEuropean Journal of Ophthalmology
Volume7
Issue number3
DOIs
StatePublished - 1997
Externally publishedYes

Keywords

  • Aspergillosis
  • Chorio-retinitis
  • Endophthalmitis
  • Eye disease
  • Fungal infection

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