Neighbor effects in the mutation of ochre triplets in the T4rII gene

Y. Salts*, A. Ronen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

In 15 sites in the T4rII gene, mutation from the ochre (UAA) codon to amber (UAG), opal (UGA) and the wild-type was measured with and without 2-aminopurine treatment. It is shown that a particular base pair in the DNA may show variable mutability, depending on its nearest neighbors. Also, similar base pairs at different sites in the gene can vary in their mutability despite the fact that they are flanked by similar neighbors.

Original languageEnglish
Pages (from-to)109-113
Number of pages5
JournalMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Volume13
Issue number2
DOIs
StatePublished - Oct 1971

Fingerprint

Dive into the research topics of 'Neighbor effects in the mutation of ochre triplets in the T4rII gene'. Together they form a unique fingerprint.

Cite this