TY - JOUR
T1 - Neurogenesis in adult rat dorsal root ganglia
AU - Devor, Marshall
AU - Govrin-Lippmann, Ruth
PY - 1985/10/24
Y1 - 1985/10/24
N2 - Nerve cells in mammalian species, including primary sensory neurons in the dorsal root ganglia (DRGs), are thought to be generated pre- or perinatally. The only known exceptions are olfactory receptor cells and some cortical microneurons. We now report results of experiments in which the number of neurons in the L4 and L5 DRGs of normal adult rats was counted from serial 10-μm paraffin sections stained with cresyl violet. Contrary to expectations, we found that there is a gradual increase in the number of DRG neurons as the animals age. The neuronal population nearly doubles over the adult life of the animal.
AB - Nerve cells in mammalian species, including primary sensory neurons in the dorsal root ganglia (DRGs), are thought to be generated pre- or perinatally. The only known exceptions are olfactory receptor cells and some cortical microneurons. We now report results of experiments in which the number of neurons in the L4 and L5 DRGs of normal adult rats was counted from serial 10-μm paraffin sections stained with cresyl violet. Contrary to expectations, we found that there is a gradual increase in the number of DRG neurons as the animals age. The neuronal population nearly doubles over the adult life of the animal.
KW - dorsal root ganglion
KW - nerve
KW - neurogenesis
KW - rat
UR - https://www.scopus.com/pages/publications/0022340703
U2 - 10.1016/0304-3940(85)90423-9
DO - 10.1016/0304-3940(85)90423-9
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C2 - 4080254
AN - SCOPUS:0022340703
SN - 0304-3940
VL - 61
SP - 189
EP - 194
JO - Neuroscience Letters
JF - Neuroscience Letters
IS - 1-2
ER -