Neurosporaside, a tetraglycosylated sphingolipid from neurospora crassa

Valeria Costantino; Alfonso Mangoni; Roberta Teta; Galia Kra-Oz; Oded Yarden

doi:10.1021/np1009493

Neurosporaside, a tetraglycosylated sphingolipid from neurospora crassa

Valeria Costantino^*, Alfonso Mangoni, Roberta Teta, Galia Kra-Oz, Oded Yarden

^*Corresponding author for this work

Department of Plant Pathology and Microbiology

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The new tetraglycosylceramide neurosporaside (1a) has been isolated from the fungus Neurospora crassa. Neurosporaside is a tetraglycosylated glycosphingolipid characterized by a sugar chain unprecedented among natural glycoconjugates. The structure of neurosporaside was elucidated by extensive spectroscopic analysis and microscale degradation analysis, which allowed full structure elucidation using less than 1 mg of compound.

Original language	English
Pages (from-to)	554-558
Number of pages	5
Journal	Journal of Natural Products
Volume	74
Issue number	4
DOIs	https://doi.org/10.1021/np1009493
State	Published - 25 Apr 2011

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10.1021/np1009493

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abstract = "The new tetraglycosylceramide neurosporaside (1a) has been isolated from the fungus Neurospora crassa. Neurosporaside is a tetraglycosylated glycosphingolipid characterized by a sugar chain unprecedented among natural glycoconjugates. The structure of neurosporaside was elucidated by extensive spectroscopic analysis and microscale degradation analysis, which allowed full structure elucidation using less than 1 mg of compound.",

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AU - Costantino, Valeria

AU - Mangoni, Alfonso

AU - Teta, Roberta

AU - Kra-Oz, Galia

AU - Yarden, Oded

PY - 2011/4/25

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N2 - The new tetraglycosylceramide neurosporaside (1a) has been isolated from the fungus Neurospora crassa. Neurosporaside is a tetraglycosylated glycosphingolipid characterized by a sugar chain unprecedented among natural glycoconjugates. The structure of neurosporaside was elucidated by extensive spectroscopic analysis and microscale degradation analysis, which allowed full structure elucidation using less than 1 mg of compound.

AB - The new tetraglycosylceramide neurosporaside (1a) has been isolated from the fungus Neurospora crassa. Neurosporaside is a tetraglycosylated glycosphingolipid characterized by a sugar chain unprecedented among natural glycoconjugates. The structure of neurosporaside was elucidated by extensive spectroscopic analysis and microscale degradation analysis, which allowed full structure elucidation using less than 1 mg of compound.

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Neurosporaside, a tetraglycosylated sphingolipid from neurospora crassa

Abstract

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