Neurotrophic factors and their receptors in lung development and implications in lung diseases

Limor Rubin; Collin T. Stabler; Adi Schumacher-Klinger; Cezary Marcinkiewicz; Peter I. Lelkes; Philip Lazarovici

doi:10.1016/j.cytogfr.2021.01.008

Neurotrophic factors and their receptors in lung development and implications in lung diseases

Limor Rubin
, Collin T. Stabler
, Adi Schumacher-Klinger
, Cezary Marcinkiewicz
, Peter I. Lelkes
, Philip Lazarovici^*

^*Corresponding author for this work

School of Pharmacy

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Although lung innervation has been described by many studies in humans and rodents, the regulation of the respiratory system induced by neurotrophins is not fully understood. Here, we review current knowledge on the role of neurotrophins and the expression and function of their receptors in neurogenesis, vasculogenesis and during the embryonic development of the respiratory tree and highlight key implications relevant to respiratory diseases.

Original language	English
Pages (from-to)	84-94
Number of pages	11
Journal	Cytokine and Growth Factor Reviews
Volume	59
DOIs	https://doi.org/10.1016/j.cytogfr.2021.01.008
State	Published - Jun 2021

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Ltd

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Development
Lung
Neurotrophic factors
Receptors
Respiratory diseases

Access to Document

10.1016/j.cytogfr.2021.01.008

Cite this

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title = "Neurotrophic factors and their receptors in lung development and implications in lung diseases",

abstract = "Although lung innervation has been described by many studies in humans and rodents, the regulation of the respiratory system induced by neurotrophins is not fully understood. Here, we review current knowledge on the role of neurotrophins and the expression and function of their receptors in neurogenesis, vasculogenesis and during the embryonic development of the respiratory tree and highlight key implications relevant to respiratory diseases.",

keywords = "Development, Lung, Neurotrophic factors, Receptors, Respiratory diseases",

author = "Limor Rubin and Stabler, \{Collin T.\} and Adi Schumacher-Klinger and Cezary Marcinkiewicz and Lelkes, \{Peter I.\} and Philip Lazarovici",

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year = "2021",

month = jun,

doi = "10.1016/j.cytogfr.2021.01.008",

language = "אנגלית",

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AU - Rubin, Limor

AU - Stabler, Collin T.

AU - Schumacher-Klinger, Adi

AU - Marcinkiewicz, Cezary

AU - Lelkes, Peter I.

AU - Lazarovici, Philip

PY - 2021/6

Y1 - 2021/6

N2 - Although lung innervation has been described by many studies in humans and rodents, the regulation of the respiratory system induced by neurotrophins is not fully understood. Here, we review current knowledge on the role of neurotrophins and the expression and function of their receptors in neurogenesis, vasculogenesis and during the embryonic development of the respiratory tree and highlight key implications relevant to respiratory diseases.

AB - Although lung innervation has been described by many studies in humans and rodents, the regulation of the respiratory system induced by neurotrophins is not fully understood. Here, we review current knowledge on the role of neurotrophins and the expression and function of their receptors in neurogenesis, vasculogenesis and during the embryonic development of the respiratory tree and highlight key implications relevant to respiratory diseases.

KW - Development

KW - Lung

KW - Neurotrophic factors

KW - Receptors

KW - Respiratory diseases

UR - https://www.scopus.com/pages/publications/85100975327

U2 - 10.1016/j.cytogfr.2021.01.008

DO - 10.1016/j.cytogfr.2021.01.008

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AN - SCOPUS:85100975327

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VL - 59

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EP - 94

JO - Cytokine and Growth Factor Reviews

JF - Cytokine and Growth Factor Reviews

ER -

Neurotrophic factors and their receptors in lung development and implications in lung diseases

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

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