Neutrophil, quo vadis?

Jadwiga Jablonska*, Zvi Granot

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

30 Scopus citations

Abstract

Neutrophils were traditionally considered to be a homogeneous population of terminally differentiated cells with very defined roles in inflammation and fighting infections. However, recent advances in neutrophil research challenge this limited view and demonstrate that neutrophils are highly versatile, play different roles in various pathologic scenarios, and are heterogeneous. With this, it is becoming clear that one term—“neutrophil”—is too general, and more precise nomenclature is urgently required. In this mini review, we discuss the knowns and unknowns in neutrophil terminology and highlight the critical questions that should be addressed for the establishment of clear neutrophil nomenclature.

Original languageAmerican English
Pages (from-to)685-688
Number of pages4
JournalJournal of Leukocyte Biology
Volume102
Issue number3
DOIs
StatePublished - Sep 2017

Bibliographical note

Publisher Copyright:
© Society for Leukocyte Biology.

Keywords

  • Low density neutrophils
  • Neutrophil subsets
  • Normal density neutrophils

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