New prospects for noninvasive blood monitoring based on effect of RBC aggregation

L. D. Shvartsman, I. Fine, D. A. Romanov

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Our analysis of spectral behavior of time-variant optical characteristics caused by RBC aggregation is applied to issues of non-invasive blood monitoring. Modulations of blood flow cause the change in geometry of RBC aggregates and corresponding variance of light scattering. This changes cause the variation of optical transmission, reflection, and polarization of outcoming light. The last can be translated back in absorption coefficients of various blood constituents, refractive index mismatch, etc. For instance, in case of long occlusion simultaneous measurements of both the azimuthal angle and the ellipticity of outcoming light can provide sufficient data to determine the blood glucose.

Original languageEnglish
Title of host publicationComplex Dynamics and Fluctuations in Biomedical Photonics V
DOIs
StatePublished - 2008
EventComplex Dynamics and Fluctuations in Biomedical Photonics V - San Jose, CA, United States
Duration: 19 Jan 200821 Jan 2008

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6855
ISSN (Print)1605-7422

Conference

ConferenceComplex Dynamics and Fluctuations in Biomedical Photonics V
Country/TerritoryUnited States
CitySan Jose, CA
Period19/01/0821/01/08

Keywords

  • Light scattering
  • Pulse oximetry
  • RBC aggregation
  • Whole blood

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