New tailor-made biodegradable polymeric biomaterials

D. Cohn*

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

Abstract

Biodegradable polymers are being used in an increasingly large number of biomedical applications, such as drug-releasing implants, bioadsorbable surgical sutures, and more novel applications, e.g. the adsorbable component in selectively biodegradable vascular grafts. The most indispensable attribute of a biodegradable material relates to the biocompatibility of both the polymer at implantation time and the products of its degradation process. Additional parameters which plan an important role include the mechanical properties of the material and, for most applications, the matching of the polymer biodegradation kinetics to that of the healing process. Our objective was to design, synthesize and characterize a series of segmented block copolymers, in which partially crystalline, biodegradable polyesters create the hard domains, while the elastic response of the system is mainly provided by flexible poly(ether glycol) chains, (e.g. polyethylene oxide, polypropylene oxide, polytetramethylene oxide.

Original languageEnglish
Pages (from-to)498
Number of pages1
JournalAmerican Chemical Society, Polymer Preprints, Division of Polymer Chemistry
Volume30
Issue number1
StatePublished - Apr 1989
EventPapers Presented at the Dallas, Texas Meeting - Dallas, TX, USA
Duration: 9 Apr 198914 Apr 1989

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