We describe two patients with epilepsy who presented with nonepileptic seizures (NES) when started on levetiracetam (LEV), which disappeared or significantly decreased when LEV was discontinued. NES are traditionally attributed to psychic trauma often after physical or sexual abuse, whereas the psychiatric side effects of levetiracetam largely encompass depression, hallucinations, and psychosis. We conclude that NES are a rare side effect of LEV treatment and part of the spectrum of behavioral changes observed with LEV treatment.
Bibliographical noteFunding Information:
This work was supported by the following grants: SNF 320030-122073, 320030-113766, 320030-118385 , SPUM grants 33CM30-124089 , and 33CM30-124115 .
- Nonepileptic seizures
- Psychogenic seizures
- Side effects