Normal tissue response to localized deep microwave hyperthermia in the rabbit's prostate: A preclinical study

A. Yerushalmi; Z. Shpirer; I. Hod; F. Gottesfeld; D. D. Bass

doi:10.1016/0360-3016(83)90213-4

Normal tissue response to localized deep microwave hyperthermia in the rabbit's prostate: A preclinical study

A. Yerushalmi^*, Z. Shpirer, I. Hod, F. Gottesfeld, D. D. Bass

^*Corresponding author for this work

Department of Animal Sciences

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Experiments were performed to determine the response of normal tissues of the rectal cavity and the prostate to localized 2.45 GHz microwave deep hyperthermia. Hyperthermia at 43°C was delivered by means of a coaxial probe in the rectal cavity for 30 min. once or twice at an interval of 2 days. Normal tissues of the rectum, urinary bladder, and prostate were histologically examined up to three months after treatments. In almost all of the treated animals no tissue and organ injury resulted from localized deep hyperthermia at 43°C. This treatment appears to be safe for the treatment of carcinoma of the prostate.

Original language	English
Pages (from-to)	77-82
Number of pages	6
Journal	International Journal of Radiation Oncology Biology Physics
Volume	9
Issue number	1
DOIs	https://doi.org/10.1016/0360-3016(83)90213-4
State	Published - Jan 1983

Keywords

Localized deep microwave hyperthermia
Normal tissue
Prostate

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10.1016/0360-3016(83)90213-4

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AU - Bass, D. D.

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AB - Experiments were performed to determine the response of normal tissues of the rectal cavity and the prostate to localized 2.45 GHz microwave deep hyperthermia. Hyperthermia at 43°C was delivered by means of a coaxial probe in the rectal cavity for 30 min. once or twice at an interval of 2 days. Normal tissues of the rectum, urinary bladder, and prostate were histologically examined up to three months after treatments. In almost all of the treated animals no tissue and organ injury resulted from localized deep hyperthermia at 43°C. This treatment appears to be safe for the treatment of carcinoma of the prostate.

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Normal tissue response to localized deep microwave hyperthermia in the rabbit's prostate: A preclinical study

Abstract

Keywords

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