Novel Dominant Rhodopsin Mutation Triggers Two Mechanisms of Retinal Degeneration and Photoreceptor Desensitization

Keyphrases

• Arrestin 100%
• Desensitization 100%
• Photoreceptor Cells 100%
• Retinal Degeneration 100%
• Rhodopsin mutation 100%
• Rod Opsin 75%
• Rhodopsin 50%
• Drosophilidae 50%
• Night Blindness 50%
• Constitutive Behavior 50%
• Apoptosis 25%
• Photoreceptor 25%
• Protein Complex 25%
• Mutant Protein 25%
• Active Form 25%
• Constitutively Active 25%
• Histology 25%
• Dominant mutation 25%
• Cell Apoptosis 25%
• Retinal Diseases 25%
• Single-unit Recording 25%
• Opsin 25%
• Light-independent 25%
• Phototransduction Cascade 25%
• Autosomal Dominant Retinitis pigmentosa 25%
• Pathological Pathways 25%
• Photoreceptor Cell Death 25%
• Transgenic Xenopus 25%
• ARR2 25%
• Deep Pseudopupil 25%
• Cytosol 25%
• Elevated Levels 25%
• Genetic Screen 25%
• Single-point mutation 25%
• Opsin Protein 25%

Biochemistry, Genetics and Molecular Biology

• Rhodopsin 100%
• Photoreceptor Cell 100%
• Arrestin 80%
• Opsin 80%
• Programmed Cell Death 40%
• Fruit Fly 40%
• Transgenics 20%
• Autosomal Dominant Inheritance 20%
• Protein Complexes 20%
• Animal Model 20%
• Genetic Screen 20%
• Mutant Protein 20%
• Cell Death 20%
• Xenopus 20%
• Whole Cell Patch Clamp 20%
• Retinitis pigmentosa 20%
• Phototransduction 20%

Neuroscience

• Photoreceptor 100%
• Rhodopsin 100%
• Retinal Degeneration 100%
• Retina S Antigen 80%
• Scotopsin 60%
• Programmed Cell Death 40%
• Cell Death 20%
• Protein Complexes 20%
• Mutant Protein 20%
• Retinal Disease 20%
• Opsin 20%
• Retinitis pigmentosa 20%
• Phototransduction 20%
• Histology 20%
• Genetics 20%