Novel matrix metallo-proteinase (MMP-2) phosphonoboronate inhibitors

Inna Pergament, Reuven Reich, Morris Srebnik*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

A series of novel phosphonoboronates consisting of PC1B, PCnB, PC(X)CnB, and PCC=CB derivatives were evaluated as MMP-2 inhibitors. Structure-activity relationships (SARs) data for the compounds were discovered and are discussed.

Original languageEnglish
Pages (from-to)1215-1218
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume12
Issue number8
DOIs
StatePublished - 22 Apr 2002

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