Novel matrix metallo-proteinase (MMP-2) phosphonoboronate inhibitors

Inna Pergament; Reuven Reich; Morris Srebnik

doi:10.1016/S0960-894X(02)00110-5

Novel matrix metallo-proteinase (MMP-2) phosphonoboronate inhibitors

Inna Pergament
, Reuven Reich
, Morris Srebnik^*

^*Corresponding author for this work

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

A series of novel phosphonoboronates consisting of PC₁B, PC_nB, PC(X)C_nB, and PCC=CB derivatives were evaluated as MMP-2 inhibitors. Structure-activity relationships (SARs) data for the compounds were discovered and are discussed.

Original language	English
Pages (from-to)	1215-1218
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	12
Issue number	8
DOIs	https://doi.org/10.1016/S0960-894X(02)00110-5
State	Published - 22 Apr 2002

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title = "Novel matrix metallo-proteinase (MMP-2) phosphonoboronate inhibitors",

abstract = "A series of novel phosphonoboronates consisting of PC1B, PCnB, PC(X)CnB, and PCC=CB derivatives were evaluated as MMP-2 inhibitors. Structure-activity relationships (SARs) data for the compounds were discovered and are discussed.",

author = "Inna Pergament and Reuven Reich and Morris Srebnik",

year = "2002",

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AU - Reich, Reuven

AU - Srebnik, Morris

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N2 - A series of novel phosphonoboronates consisting of PC1B, PCnB, PC(X)CnB, and PCC=CB derivatives were evaluated as MMP-2 inhibitors. Structure-activity relationships (SARs) data for the compounds were discovered and are discussed.

AB - A series of novel phosphonoboronates consisting of PC1B, PCnB, PC(X)CnB, and PCC=CB derivatives were evaluated as MMP-2 inhibitors. Structure-activity relationships (SARs) data for the compounds were discovered and are discussed.

UR - https://www.scopus.com/pages/publications/0037156351

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JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 8

ER -

Novel matrix metallo-proteinase (MMP-2) phosphonoboronate inhibitors

Abstract

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