Novel parotid sialo-cone-beam computerized tomography features in patients with suspected Sjogren’s syndrome

Naama Keshet*, Adi Aricha, Silvina Friedlander-Barenboim, Doron J. Aframian, Chen Nadler

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations


    Objective: Sjogren’s syndrome (SjS) causes salivary gland impairment leading to oral dryness. Parotid sialo-cone-beam computerized tomography (sialo-CBCT) demonstrates ductal architecture and to a lesser extent gland activity. This study characterizes radiographic features of patients suspected for SjS and looks for a possible correlation with the diagnosis of SjS. Methods: The clinical and radiographic data of suspected SjS/dry mouth patients referred for sialo-CBCT in 2011–2014 were reviewed retrospectively. Two observers studied the scans for various radiographic features including duct morphology, level of branching, ductopenia and sialectasia. These features were analysed taking the specific clinical data and two sets of SjS criteria: The 2002 American-European Consensus Group (AECG) and the 2012 American College of Rheumatology (ACR) Group. Results: Sialo-CBCT scans of 67-referred patients suffering from dry mouth (115 parotid glands) were included. Intraradiographic association was found between ductopenia and all other radiographic parameters. Minimal, yet important, radiographic differences were found between left and right parotid glands. AECG-confirmed-SjS patients showed strong correlation with radiographic features, whereas ACR 2012-confirmed-SjS patients did not. Conclusion: Sialo-CBCT demonstrates novel radiographic features which may clarify the diagnosis of SjS. Further studies are needed to determine the role of sialo-CBCT in diagnosis of SjS.

    Original languageAmerican English
    Pages (from-to)126-132
    Number of pages7
    JournalOral Diseases
    Issue number1
    StatePublished - Jan 2019

    Bibliographical note

    Publisher Copyright:
    © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. All rights reserved


    • Sjogren’s syndrome
    • cone-beam computerized tomography
    • ductopenia
    • salivary ducts
    • sialectasis
    • sialography


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