Nucleosome mapping in plasma DNA predicts cancer gene expression

Muhammed Murtaza; Carlos Caldas

doi:10.1038/ng.3686

Nucleosome mapping in plasma DNA predicts cancer gene expression

Muhammed Murtaza
, Carlos Caldas

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

Abstract

A new study demonstrates that genomic sequencing coverage of plasma DNA fragments around transcription start sites reflects the expression levels of genes in corresponding tumors. This approach may enable noninvasive monitoring of treatment-induced changes in gene expression for patients with cancer.

Original language	English
Pages (from-to)	1105-1106
Number of pages	2
Journal	Nature Genetics
Volume	48
Issue number	10
DOIs	https://doi.org/10.1038/ng.3686
State	Published - 1 Oct 2016
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2016 Nature America, Inc. All rights reserved.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1038/ng.3686

Cite this

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Nucleosome mapping in plasma DNA predicts cancer gene expression

Abstract

Bibliographical note

UN SDGs

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