Abstract
Progerin, a mutated form of lamin A, causes the premature ageing disease Hutchinson-Gilford progeria syndrome and is also involved in normal ageing. Progerin accumulation leads to distinct chromatin-related defects and the NURD complex appears to affect ageing-related chromatin defects.
Original language | English |
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Pages (from-to) | 1176-1177 |
Number of pages | 2 |
Journal | Nature Cell Biology |
Volume | 11 |
Issue number | 10 |
DOIs | |
State | Published - 2009 |