Abstract
Two aspects of erythroid differentiation and maturation are referred to to illustrate the complexity and immense refinement of the events leading from the erythroid-committed stem cell to the mature erythrocyte: The evolution of a soluble cell component is indispensable for a non-hemoglobin producing erythroid progenitor cell to transform itself into one which elaborates hemoglobin in abundance. A casual relationship is strongly supported between the cellular hemoglobin concentration and the cessation of nucleic acid synthesis in the maturing erythroid cell.
| Original language | English |
|---|---|
| Pages (from-to) | 34-42 |
| Number of pages | 9 |
| Journal | New Istanbul Contribution to Clinical Science |
| Volume | 12 |
| Issue number | 1 |
| State | Published - 1977 |