Occurrence of CNS demyelinating disease in patients with myasthenia gravis

Marc Gotkine; Yakov Fellig; Oded Abramsky

doi:10.1212/01.wnl.0000234142.41728.a0

Occurrence of CNS demyelinating disease in patients with myasthenia gravis

Marc Gotkine^*, Yakov Fellig, Oded Abramsky

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

An increased incidence of multiple sclerosis (MS) has been reported in patients with myasthenia gravis (MG). We reviewed records of 214 patients with MG. CNS demyelinating disease (CNSDD) occurred in five patients (2.3%). CNSDD always occurred after the diagnosis of MG. Myelitis (including recurrent myelitis) was the most common CNS manifestation. All patients had antinuclear antibodies. CNSDD occurs more frequently in patients with MG and may be related to immune-modulating treatments including thymectomy.

Original language	English
Pages (from-to)	881-883
Number of pages	3
Journal	Neurology
Volume	67
Issue number	5
DOIs	https://doi.org/10.1212/01.wnl.0000234142.41728.a0
State	Published - Sep 2006
Externally published	Yes

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abstract = "An increased incidence of multiple sclerosis (MS) has been reported in patients with myasthenia gravis (MG). We reviewed records of 214 patients with MG. CNS demyelinating disease (CNSDD) occurred in five patients (2.3\%). CNSDD always occurred after the diagnosis of MG. Myelitis (including recurrent myelitis) was the most common CNS manifestation. All patients had antinuclear antibodies. CNSDD occurs more frequently in patients with MG and may be related to immune-modulating treatments including thymectomy.",

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AB - An increased incidence of multiple sclerosis (MS) has been reported in patients with myasthenia gravis (MG). We reviewed records of 214 patients with MG. CNS demyelinating disease (CNSDD) occurred in five patients (2.3%). CNSDD always occurred after the diagnosis of MG. Myelitis (including recurrent myelitis) was the most common CNS manifestation. All patients had antinuclear antibodies. CNSDD occurs more frequently in patients with MG and may be related to immune-modulating treatments including thymectomy.

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Occurrence of CNS demyelinating disease in patients with myasthenia gravis

Abstract

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