TY - JOUR
T1 - On the role of water in molecular recognition and self-assembly
AU - Ben-Naim, A.
PY - 1987/6
Y1 - 1987/6
N2 - The conventional concept of hydrophobic interaction is generalized to include any kind of solvent-induced effects on the binding of two or more solutes in aqueous solutions. Specifically, we focus on the role of hydrogen-bonding between the solutes and solvent molecules. A qualitative examination of the solute-solvent hydrogen-bonding effect on molecular recognition, self-assembly, and stabilization of biopolymers shows that these effects might be quite large and possible more important than direct interactions between solute particles.
AB - The conventional concept of hydrophobic interaction is generalized to include any kind of solvent-induced effects on the binding of two or more solutes in aqueous solutions. Specifically, we focus on the role of hydrogen-bonding between the solutes and solvent molecules. A qualitative examination of the solute-solvent hydrogen-bonding effect on molecular recognition, self-assembly, and stabilization of biopolymers shows that these effects might be quite large and possible more important than direct interactions between solute particles.
KW - Molecular recognition
KW - hydrophobic interaction
KW - role of water
KW - self-assembly
KW - solvent-induced effects
UR - http://www.scopus.com/inward/record.url?scp=0012016434&partnerID=8YFLogxK
U2 - 10.1007/BF02861534
DO - 10.1007/BF02861534
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AN - SCOPUS:0012016434
SN - 0370-0089
VL - 98
SP - 357
EP - 377
JO - Proceedings of the Indian Academy of Sciences: Chemical Sciences
JF - Proceedings of the Indian Academy of Sciences: Chemical Sciences
IS - 5-6
ER -