Abstract
The conventional concept of hydrophobic interaction is generalized to include any kind of solvent-induced effects on the binding of two or more solutes in aqueous solutions. Specifically, we focus on the role of hydrogen-bonding between the solutes and solvent molecules. A qualitative examination of the solute-solvent hydrogen-bonding effect on molecular recognition, self-assembly, and stabilization of biopolymers shows that these effects might be quite large and possible more important than direct interactions between solute particles.
| Original language | English |
|---|---|
| Pages (from-to) | 357-377 |
| Number of pages | 21 |
| Journal | Proceedings of the Indian Academy of Sciences: Chemical Sciences |
| Volume | 98 |
| Issue number | 5-6 |
| DOIs | |
| State | Published - Jun 1987 |
Keywords
- Molecular recognition
- hydrophobic interaction
- role of water
- self-assembly
- solvent-induced effects