Oncornavirus like particles released from arginine deprived human lymphoblastoid cell lines

M. Kotler; H. Balabanova; E. Weinberg; A. Friedmann; Y. Becker

doi:10.1073/pnas.72.11.4592

Oncornavirus like particles released from arginine deprived human lymphoblastoid cell lines

M. Kotler
, H. Balabanova
, E. Weinberg
, A. Friedmann
, Y. Becker

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Type C RNA tumor virus particles were released from three different human lymphoblastoid cell lines after incubation in arginine deficient medium. The released virus like particles were characterized by their ability to band in sucrose gradients at a density of 1.16-1.18 g/ml; by the presence of an RNA directed DNA polymerase activity resembling that of the oncornaviruses; and by isolation of cores that band at a density of 1.26-1.27 g/ml in sucrose gradients. Examination of the arginine human lymphoblastoid cell strain P ₃HR 1 by electron microscopy revealed the presence of C type particles in the intracellular spaces.

Original language	English
Pages (from-to)	4592-4596
Number of pages	5
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	72
Issue number	11
DOIs	https://doi.org/10.1073/pnas.72.11.4592
State	Published - 1975

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10.1073/pnas.72.11.4592

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title = "Oncornavirus like particles released from arginine deprived human lymphoblastoid cell lines",

abstract = "Type C RNA tumor virus particles were released from three different human lymphoblastoid cell lines after incubation in arginine deficient medium. The released virus like particles were characterized by their ability to band in sucrose gradients at a density of 1.16-1.18 g/ml; by the presence of an RNA directed DNA polymerase activity resembling that of the oncornaviruses; and by isolation of cores that band at a density of 1.26-1.27 g/ml in sucrose gradients. Examination of the arginine human lymphoblastoid cell strain P 3HR 1 by electron microscopy revealed the presence of C type particles in the intracellular spaces.",

author = "M. Kotler and H. Balabanova and E. Weinberg and A. Friedmann and Y. Becker",

year = "1975",

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T1 - Oncornavirus like particles released from arginine deprived human lymphoblastoid cell lines

AU - Kotler, M.

AU - Balabanova, H.

AU - Weinberg, E.

AU - Friedmann, A.

AU - Becker, Y.

PY - 1975

Y1 - 1975

N2 - Type C RNA tumor virus particles were released from three different human lymphoblastoid cell lines after incubation in arginine deficient medium. The released virus like particles were characterized by their ability to band in sucrose gradients at a density of 1.16-1.18 g/ml; by the presence of an RNA directed DNA polymerase activity resembling that of the oncornaviruses; and by isolation of cores that band at a density of 1.26-1.27 g/ml in sucrose gradients. Examination of the arginine human lymphoblastoid cell strain P 3HR 1 by electron microscopy revealed the presence of C type particles in the intracellular spaces.

AB - Type C RNA tumor virus particles were released from three different human lymphoblastoid cell lines after incubation in arginine deficient medium. The released virus like particles were characterized by their ability to band in sucrose gradients at a density of 1.16-1.18 g/ml; by the presence of an RNA directed DNA polymerase activity resembling that of the oncornaviruses; and by isolation of cores that band at a density of 1.26-1.27 g/ml in sucrose gradients. Examination of the arginine human lymphoblastoid cell strain P 3HR 1 by electron microscopy revealed the presence of C type particles in the intracellular spaces.

UR - https://www.scopus.com/pages/publications/0016802795

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JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

IS - 11

ER -

Oncornavirus like particles released from arginine deprived human lymphoblastoid cell lines

Abstract

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