Abstract
Oxidative bromination of activated aromatic compounds using alkali metal bromide salts and aqueous nitric acid to the corresponding bromo-derivatives is achieved in a liquid-liquid, two-phase system under ambient conditions. Nitric acid offers a dual function of an oxidant as well as a proton donor, which is essential for oxidative bromination using metal bromide salts. Bromination as well as chlorination could be accomplished with this simple system.
Original language | English |
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Pages (from-to) | 568-570 |
Number of pages | 3 |
Journal | Organic Process Research and Development |
Volume | 8 |
Issue number | 4 |
DOIs | |
State | Published - Jul 2004 |