Open Chromatin, Epigenetic Plasticity, and Nuclear Organization in Pluripotency

Sharon Schlesinger, Eran Meshorer*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

65 Scopus citations


Pluripotent embryonic stem cells are considered to have open and accessible chromatin relative to differentiated cells. Schlesinger and Meshorer review chromatin and epigenetic features in 2i- versus serum-grown conditions to come to a clearer picture of the genuine characteristics of pluripotency as opposed to artifacts of culture condition.

Original languageAmerican English
Pages (from-to)135-150
Number of pages16
JournalDevelopmental Cell
Issue number2
StatePublished - 28 Jan 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Inc.


  • 2i
  • chromatin
  • chromatin plasticity
  • differentiation
  • embryonic stem cells
  • epigenetics
  • ground state
  • naive
  • nuclear plasticity
  • pluripotency
  • serum


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