Optical detection of glucose and acetylcholine esterase inhibitors by H2O2-sensitive CdSe/ZnS quantum dots

Ron Gill; Lily Bahshi; Ronit Freeman; Itamar Willner

doi:10.1002/anie.200704794

Optical detection of glucose and acetylcholine esterase inhibitors by H₂O₂-sensitive CdSe/ZnS quantum dots

Ron Gill^*
, Lily Bahshi
, Ronit Freeman
, Itamar Willner

^*Corresponding author for this work

Institute of Chemistry

Research output: Contribution to journal › Article › peer-review

230 Scopus citations

Abstract

(Figure Presented) The coupling of oxidases with fluorophore-labeled CdSe/ZnS quantum dots enables the ratiometric fluorescence analysis of enzyme activities and their substrates by the interaction between the biocatalytically generated H₂O₂ and the quantum dots. The method has been applied to the analyis of glucose and the inhibition of acetylcholine esterase.

Original language	English
Pages (from-to)	1676-1679
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	47
Issue number	9
DOIs	https://doi.org/10.1002/anie.200704794
State	Published - 15 Feb 2008

Keywords

Biosensors
Enzymes
Nanobiotechnology
Nanoparticles
Quantum dots

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10.1002/anie.200704794

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abstract = "(Figure Presented) The coupling of oxidases with fluorophore-labeled CdSe/ZnS quantum dots enables the ratiometric fluorescence analysis of enzyme activities and their substrates by the interaction between the biocatalytically generated H2O2 and the quantum dots. The method has been applied to the analyis of glucose and the inhibition of acetylcholine esterase.",

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author = "Ron Gill and Lily Bahshi and Ronit Freeman and Itamar Willner",

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AU - Gill, Ron

AU - Bahshi, Lily

AU - Freeman, Ronit

AU - Willner, Itamar

PY - 2008/2/15

Y1 - 2008/2/15

N2 - (Figure Presented) The coupling of oxidases with fluorophore-labeled CdSe/ZnS quantum dots enables the ratiometric fluorescence analysis of enzyme activities and their substrates by the interaction between the biocatalytically generated H2O2 and the quantum dots. The method has been applied to the analyis of glucose and the inhibition of acetylcholine esterase.

AB - (Figure Presented) The coupling of oxidases with fluorophore-labeled CdSe/ZnS quantum dots enables the ratiometric fluorescence analysis of enzyme activities and their substrates by the interaction between the biocatalytically generated H2O2 and the quantum dots. The method has been applied to the analyis of glucose and the inhibition of acetylcholine esterase.

KW - Biosensors

KW - Enzymes

KW - Nanobiotechnology

KW - Nanoparticles

KW - Quantum dots

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AN - SCOPUS:41049086354

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JF - Angewandte Chemie - International Edition

IS - 9

ER -

Optical detection of glucose and acetylcholine esterase inhibitors by H₂O₂-sensitive CdSe/ZnS quantum dots

Abstract

Keywords

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