Oral mucosal changes associated with primary diseases in other body systems

Sharon Elad*, Yehuda Zadik, Jack G. Caton, Joel B. Epstein

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

24 Scopus citations


Systemic diseases may manifest in the oral cavity. This chapter reviews the oral mucosal pathology in blood diseases, gastrohepatic diseases, kidney diseases, immunologic and connective tissue diseases, endocrine diseases, pulmonary diseases, nutritional deficiencies, dermatologic diseases, as well as cancer-associated oral mucosal conditions. The oral mucosa is one of the most commonly affected tissues and may present with unique clinical appearances. Oral mucosal involvement may be the first presentation of the systemic disease or reflect activity or progression of the primary condition. Therefore, it is of importance to be familiar with oral mucosal manifestations of these systemic diseases.

Original languageAmerican English
Pages (from-to)28-48
Number of pages21
JournalPeriodontology 2000
Issue number1
StatePublished - Jun 2019

Bibliographical note

Publisher Copyright:
© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd


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