TY - GEN
T1 - Orchestration of DNA methylation
AU - Cedar, Howard
PY - 2008
Y1 - 2008
N2 - DNA methylation plays an important role in gene regulation. In order to gain a better understanding of the rules governing this epigenetic modification, we have used microarray technology to map DNA methylation in the human genome. This analysis has helped decipher the DNA sequences involved in setting up the basic global methylation pattern in the early embryo and has revealed the full range of methylation changes that occur in a programmed manner during development. These studies also help explain how specific CpG island genes are targeted for de novo methylation in cancer. About the keynote speaker. Dr. Howard Cedar was born in New York, received a B.Sc. degree in mathematics from M.I.T. and M.D., Ph.D. degrees from N.Y.U. After an internship he continued as a Public health fellow at the N.I.H. In 1973 he immigrated to Israel where he became a full Professor of Molecular Biology in 1981. Dr. Cedar has received a number of awards including the Israel Prize and the Wolf Prize for Medicine, and is a member of the Israel Academy of Sciences.
AB - DNA methylation plays an important role in gene regulation. In order to gain a better understanding of the rules governing this epigenetic modification, we have used microarray technology to map DNA methylation in the human genome. This analysis has helped decipher the DNA sequences involved in setting up the basic global methylation pattern in the early embryo and has revealed the full range of methylation changes that occur in a programmed manner during development. These studies also help explain how specific CpG island genes are targeted for de novo methylation in cancer. About the keynote speaker. Dr. Howard Cedar was born in New York, received a B.Sc. degree in mathematics from M.I.T. and M.D., Ph.D. degrees from N.Y.U. After an internship he continued as a Public health fellow at the N.I.H. In 1973 he immigrated to Israel where he became a full Professor of Molecular Biology in 1981. Dr. Cedar has received a number of awards including the Israel Prize and the Wolf Prize for Medicine, and is a member of the Israel Academy of Sciences.
UR - http://www.scopus.com/inward/record.url?scp=47249149648&partnerID=8YFLogxK
U2 - 10.1007/978-3-540-78839-3_6
DO - 10.1007/978-3-540-78839-3_6
M3 - ???researchoutput.researchoutputtypes.contributiontobookanthology.conference???
AN - SCOPUS:47249149648
SN - 3540788387
SN - 9783540788386
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 65
BT - Research in Computational Molecular Biology - 12th Annual International Conference, RECOMB 2008, Proceedings
T2 - "12th Annual InternationalConference on REsearch in COmputational Molecular Biology, RECOMB 2008"
Y2 - 30 March 2008 through 2 April 2008
ER -
