Orchestration of DNA methylation

Howard Cedar

doi:10.1007/978-3-540-78839-3_6

Orchestration of DNA methylation

Howard Cedar^*

^*Corresponding author for this work

Institute for Medical Research Israel-Canada (IMRIC)

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

DNA methylation plays an important role in gene regulation. In order to gain a better understanding of the rules governing this epigenetic modification, we have used microarray technology to map DNA methylation in the human genome. This analysis has helped decipher the DNA sequences involved in setting up the basic global methylation pattern in the early embryo and has revealed the full range of methylation changes that occur in a programmed manner during development. These studies also help explain how specific CpG island genes are targeted for de novo methylation in cancer. About the keynote speaker. Dr. Howard Cedar was born in New York, received a B.Sc. degree in mathematics from M.I.T. and M.D., Ph.D. degrees from N.Y.U. After an internship he continued as a Public health fellow at the N.I.H. In 1973 he immigrated to Israel where he became a full Professor of Molecular Biology in 1981. Dr. Cedar has received a number of awards including the Israel Prize and the Wolf Prize for Medicine, and is a member of the Israel Academy of Sciences.

Original language	English
Title of host publication	Research in Computational Molecular Biology - 12th Annual International Conference, RECOMB 2008, Proceedings
Pages	65
Number of pages	1
DOIs	https://doi.org/10.1007/978-3-540-78839-3_6
State	Published - 2008
Event	"12th Annual InternationalConference on REsearch in COmputational Molecular Biology, RECOMB 2008" - Singapore, Singapore Duration: 30 Mar 2008 → 2 Apr 2008

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume	4955 LNBI
ISSN (Print)	0302-9743
ISSN (Electronic)	1611-3349

Conference

Conference	"12th Annual InternationalConference on REsearch in COmputational Molecular Biology, RECOMB 2008"
Country/Territory	Singapore
City	Singapore
Period	30/03/08 → 2/04/08

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1007/978-3-540-78839-3_6

Cite this

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title = "Orchestration of DNA methylation",

abstract = "DNA methylation plays an important role in gene regulation. In order to gain a better understanding of the rules governing this epigenetic modification, we have used microarray technology to map DNA methylation in the human genome. This analysis has helped decipher the DNA sequences involved in setting up the basic global methylation pattern in the early embryo and has revealed the full range of methylation changes that occur in a programmed manner during development. These studies also help explain how specific CpG island genes are targeted for de novo methylation in cancer. About the keynote speaker. Dr. Howard Cedar was born in New York, received a B.Sc. degree in mathematics from M.I.T. and M.D., Ph.D. degrees from N.Y.U. After an internship he continued as a Public health fellow at the N.I.H. In 1973 he immigrated to Israel where he became a full Professor of Molecular Biology in 1981. Dr. Cedar has received a number of awards including the Israel Prize and the Wolf Prize for Medicine, and is a member of the Israel Academy of Sciences.",

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Cedar, H 2008, Orchestration of DNA methylation. in Research in Computational Molecular Biology - 12th Annual International Conference, RECOMB 2008, Proceedings. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 4955 LNBI, pp. 65, "12th Annual InternationalConference on REsearch in COmputational Molecular Biology, RECOMB 2008", Singapore, Singapore, 30/03/08. https://doi.org/10.1007/978-3-540-78839-3_6

Orchestration of DNA methylation. / Cedar, Howard.
Research in Computational Molecular Biology - 12th Annual International Conference, RECOMB 2008, Proceedings. 2008. p. 65 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 4955 LNBI).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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Orchestration of DNA methylation

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