TY - JOUR
T1 - Outbreak Size Distribution in Stochastic Epidemic Models
AU - Hindes, Jason
AU - Assaf, Michael
AU - Schwartz, Ira B.
N1 - Publisher Copyright:
© 2022 us.
PY - 2022/2/18
Y1 - 2022/2/18
N2 - Motivated by recent epidemic outbreaks, including those of COVID-19, we solve the canonical problem of calculating the dynamics and likelihood of extensive outbreaks in a population within a large class of stochastic epidemic models with demographic noise, including the susceptible-infected-recovered (SIR) model and its general extensions. In the limit of large populations, we compute the probability distribution for all extensive outbreaks, including those that entail unusually large or small (extreme) proportions of the population infected. Our approach reveals that, unlike other well-known examples of rare events occurring in discrete-state stochastic systems, the statistics of extreme outbreaks emanate from a full continuum of Hamiltonian paths, each satisfying unique boundary conditions with a conserved probability flux.
AB - Motivated by recent epidemic outbreaks, including those of COVID-19, we solve the canonical problem of calculating the dynamics and likelihood of extensive outbreaks in a population within a large class of stochastic epidemic models with demographic noise, including the susceptible-infected-recovered (SIR) model and its general extensions. In the limit of large populations, we compute the probability distribution for all extensive outbreaks, including those that entail unusually large or small (extreme) proportions of the population infected. Our approach reveals that, unlike other well-known examples of rare events occurring in discrete-state stochastic systems, the statistics of extreme outbreaks emanate from a full continuum of Hamiltonian paths, each satisfying unique boundary conditions with a conserved probability flux.
UR - http://www.scopus.com/inward/record.url?scp=85125883250&partnerID=8YFLogxK
U2 - 10.1103/physrevlett.128.078301
DO - 10.1103/physrevlett.128.078301
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C2 - 35244445
AN - SCOPUS:85125883250
SN - 0031-9007
VL - 128
JO - Physical Review Letters
JF - Physical Review Letters
IS - 7
M1 - 078301
ER -