Abstract
EIS (electrolyte-insulator-semiconductor) sensors based on the functionalization of uncoated gold nanoparticles supported on a Si/SiO 2 structure are presented. Oxygen plasma etching at moderate power (<200 W) provides a convenient and efficient way to remove organic capping agents from the gold nanoparticles without significant damage. Higher power intensities destroy the linkage between the SiO2 and the gold nanoparticles, and some of the gold nanoparticles are removed from the surface. The flat-band potential shift, i.e. the pH dependence of the gold-coated EIS sensors is similar (33 mV/pH) to the uncoated EIS pH-sensor. Lead, penicillin and glucose sensors were prepared by immobilization of β-cyclodextrin, penicillinase and glucose oxidase by various immobilization techniques.
| Original language | English |
|---|---|
| Pages (from-to) | 395-404 |
| Number of pages | 10 |
| Journal | Microchimica Acta |
| Volume | 164 |
| Issue number | 3-4 |
| DOIs | |
| State | Published - Mar 2009 |
Bibliographical note
Funding Information:The authors are grateful for the technical assistance of H.-P. Bochem and A. Besmehn for the surface characterization with HRSEM and XPS and to A. Voskevich for the very useful discussions. J. Gun thanks the Alexander von Humboldt Foundation for the financial support.
Keywords
- EIS sensor
- Field-effect device
- Functionalization
- Glucose
- Gold nanoparticles
- Lead
- Penicillin