Palatal Erythema with Histological Psoriasiform Pattern: An Enigmatic Oral Finding Shared by a Range of Conditions

Ayelet Zlotogorski Hurvitz*, Yehuda Zadik, Leon Gillman, Ori Platner, Tali Shani, Yuli Goldman, Gavriel Chaushu, Ilana Kaplan, Aviv Barzilai, Nadav Astman, Shoshana Reiter, Marilena Vered

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Long standing, asymptomatic, well-demarcated erythema of the hard palate with a histopathological psoriasiform pattern comprises a challenging diagnosis. We present a series of patients with such clinical and histological findings and discuss the possible diagnoses. We collected all patients with palatal erythematous lesions that had well-documented clinical examination. Excluded were patients with definitive diagnosis of oral infections (e.g. candidiasis), neoplastic/pre-neoplastic lesions, auto-immune diseases, reactive lesions, blood disorders and vascular malformations. Thirteen patients (six females, seven males, age range 11–56 years) were included. Histopathologically, a psoriasiform pattern was observed in all biopsied lesions. One patient was diagnosed with hereditary mucoepithelial dysplasia (HMD) and four with cutaneous psoriasis. The remaining eight patients were otherwise healthy. A combination of persistent, asymptomatic palatal erythematous lesion with psoriasis-like histopathology may represent an oral manifestation of HMD or psoriasis, concomitant to extra-oral features. In lack of any known medical background, the term "oral psoriasiform mucositis" is suggested.

Original languageAmerican English
Pages (from-to)1111-1116
Number of pages6
JournalHead and Neck Pathology
Issue number4
StatePublished - Dec 2020

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© 2020, Springer Science+Business Media, LLC, part of Springer Nature.


  • Hereditary mucoepithelial dysplasia
  • Oral psoriasiform mucositis
  • Oral psoriasis


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