TY - JOUR
T1 - Palestinian infantile visceral leishmaniasis caused by a genetic variant of Leishmania infantum belonging to a new zymodeme
AU - Bader, Khaldoun A.
AU - Schnur, Lionel F.
AU - Nasereddin, Abedelmajeed
AU - Pratlong, Francine
AU - Dedet, Jean Pierre
AU - Shaheen, Loay
AU - Yousef, Obaida
AU - Greenblatt, Charles L.
PY - 2005/6
Y1 - 2005/6
N2 - The parasites causing a Palestinian case of infantile visceral leishmaniasis (IVL) and those from four dogs from the Jenin District were identified serologically, biochemically and molecular biologically as Leishmania infantum, showing dogs act as a reservoir. The strain from the human case was distinct because of its unique 200-bp kDNA-polymerase chain reaction (PCR) component in its restriction fragment length polymorphism (RFLP) profile after digestion with the endonuclease RsaI, and by the electrophoretic mobility of its malate dehydrogenase (MDH 140), designating it the reference strain of a new zymodeme of L. infantum, MON-281.
AB - The parasites causing a Palestinian case of infantile visceral leishmaniasis (IVL) and those from four dogs from the Jenin District were identified serologically, biochemically and molecular biologically as Leishmania infantum, showing dogs act as a reservoir. The strain from the human case was distinct because of its unique 200-bp kDNA-polymerase chain reaction (PCR) component in its restriction fragment length polymorphism (RFLP) profile after digestion with the endonuclease RsaI, and by the electrophoretic mobility of its malate dehydrogenase (MDH 140), designating it the reference strain of a new zymodeme of L. infantum, MON-281.
KW - Isoenzyme analysis
KW - Leishmania infantum
KW - Palestinian authority
KW - Polymerase chain reaction
UR - http://www.scopus.com/inward/record.url?scp=20444367313&partnerID=8YFLogxK
U2 - 10.1111/j.1365-3156.2005.01419.x
DO - 10.1111/j.1365-3156.2005.01419.x
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C2 - 15941427
AN - SCOPUS:20444367313
SN - 1360-2276
VL - 10
SP - 618
EP - 620
JO - Tropical Medicine and International Health
JF - Tropical Medicine and International Health
IS - 6
ER -