Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Keyphrases

• Whole Genome 100%
• Pan-cancer Analysis 100%
• Retrotransposition 100%
• LINE-1 Retrotransposition 100%
• Cancer Genome 66%
• All Cancer 33%
• Oncogene 33%
• Tumor Suppressor Gene 33%
• Oncogenesis 33%
• Duplication 33%
• Colorectal Cancer 33%
• Retrotransposon 33%
• Human Tumors 33%
• Hereafter 33%
• Head-and-neck Cancer 33%
• Genome Project 33%
• Cancer Subtypes 33%
• Esophageal Adenocarcinoma 33%
• Event Type 33%
• Long Interspersed nuclear element-1 (LINE-1) 33%
• L1 Retrotransposition 33%
• Somatic Integration 33%
• Somatic Structural Variation 33%
• Complex Translocation 33%
• High-level Amplifications 33%

Biochemistry, Genetics and Molecular Biology

• Pan-cancer 100%
• Oncogene 50%
• Tumor Suppressor Gene 50%
• Carcinogenesis 50%
• Retrotransposon 50%
• Autosome 50%
• Long Interspersed Nuclear Element 50%

Medicine and Dentistry

• Malignant Neoplasm 100%
• Somatics 80%
• Neoplasm 20%
• Cancer 20%
• Tumor Suppressor Gene 20%
• Oncogene 20%
• Colorectal Carcinoma 20%
• Carcinogenesis 20%
• Head and Neck Cancer 20%
• Esophageal Adenocarcinoma 20%
• Autosome 20%
• Retroposon 20%